2019年8月29日 星期四

顧小培 L- arginine 控制體重

顧小培是免疫學博士,在信報寫專欄, 退休後更成立公司,介紹如何用天然食品對抗健康問題。

去顧小培的辦公室找他,他會根據你所問的健康狀況,在美國國家圖書館網頁上找出相關論文,再解釋針對這個健康問題,可以用甚麼健康食品得到幫助。
顧小培強調的,是健康食品沒有專利,所以藥廠不會去推銷,但有無數關於健康食品幫助到身體的健康問題的論文,都刊登在美國這個圖書館網頁,所以顧小培很多也會仔細串出健康食品的英文名稱,目的便是可以讓聽眾自己上網繼續查詢。


最近聽到 電台錄音, 他分享服用 L-arginine 可以達到控制體重目的。


以下是顧小培電台錄音的連結

https://www.youtube.com/watch?v=DEksIY6RiYg

 

以下是其中一篇論文


https://www.ncbi.nlm.nih.gov/pubmed/26379826 

隨便用以下search term, 便可搜索到很多相關的論文.


"L-arginine", "fat"

 

 Effect of L-arginine supplementation on insulin resistance and serum adiponectin concentration in rats with fat diet.



OBJECT:

The purpose of this study was to determine whether supplementation with L-arginine, a substrate used in the production of nitric oxide, had an effect on adiponectin concentration in rats fed a high-fat diet. The influence of L-arginine on insulin resistance was also evaluated.

MATERIALS AND METHODS:

The experiment was performed using 36 Wistar rats divided into three groups: group 1 was fed a standard diet, group 2 a high-fat (HF) diet, group 3 a HF diet supplemented with L-arginine. After 42 days, serum levels of lipids, glucose, insulin, NO, and adiponectin were measured. Insulin resistance (IR) was estimated by the Homeostasis Model Assessment (HOMA).

RESULTS:

Body mass was equal in all 3 groups, at the beginning as well as at the end of the study, however, in group 2 the amount of visceral fat was greater after 42 days. In group 3, there was a tendency for visceral fat to decrease. An increase in cholesterol, triglycerides, insulin and HOMA-IR, as well as a decrease in NO and adiponectin were seen in group 2, while in group 3, L-arginine supplementation ameliorated these disturbances.

CONCLUSIONS:

Our study shows that L-arginine supplementation in rats fed a HF diet is associated with an increase in insulin sensitivity. Our findings suggest that the underlying mechanism could be at least partially related to an increase in adiponectin concentration.
 

 

 

 

摘要

 

 目的:

本研究的目的是確定補充L-精氨酸(一種用於生產一氧化氮的底物)是否對餵食高脂肪飲食的大鼠的脂聯素濃度有影響還評估L-精氨酸對胰島素抗性的影響

方法:  使用分成三組的36只Wistar大鼠進行實驗:組1餵食標準飲食,組2餵食高脂肪(HF)飲食,組3餵食補充有L-精氨酸的HF飲食42天后,測量血清中的脂質,葡萄糖,胰島素,NO和脂聯素水平。通過穩態模型評估(HOMA)估計胰島素抵抗(IR)。

 

結果:

在研究的開始和結束時,所有3組的體重相等,然而,在第2組中,42天后內臟脂肪的量更大。在第3組中,存在內臟脂肪減少的趨勢在第2組中觀察到膽固醇,甘油三酯,胰島素和HOMA-IR的增加以及NO和脂聯素的減少,而在第3組中,補充L-精氨酸改善了這些干擾。

結論:

我們的研究表明,餵食HF飲食的大鼠補充L-精氨酸與胰島素敏感性增加有關。我們的研究結果表明,潛在的機制可能至少部分與脂聯素濃度的增加有關。



剛知道顧博士開了網店, 以後要買他介紹的健康食品, 便可以去網店購買. 

https://www.ku-dietary.hk/index.php?route=common/home 

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